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| Menopause Research Report
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| Dangers of Hormone Replacement Therapy |
| Due to an increased risk of invasive breast cancer, this July 9, 2002 press release from the National Heart, Lung and Blood Institute (NHLBI), NHLBI Stops Trial of Estrogen Plus Progestin Due to Increased Breast Cancer Risk, Lack of Overall Benefit, announced the halt of a major clinical trial being conducted by the Women's Health Initiative (WHI) on the risks and benefits of combined estrogen and progestin in healthy menopausal women. (The NHLBI plans, conducts, fosters, and supports an integrated and coordinated program of basic research, clinical investigations and trials, observational studies, and demonstration and education projects. Research is related to the causes, prevention, diagnosis, and treatment of heart, blood vessel, lung, and blood diseases; and sleep disorders.)
Results of the Women's Health Initiative Randomized Controlled Trial are detailed in the July 17, 2002 JAMA report (Journal of the American Medical Association) Risks and Benefits of Estrogen Plus Progestin in Healthy Postmenopausal Women. This report also references 43 related reports and medical abstracts. Increased Risk of Ovarian Cancer is Linked to Estrogen Replacement Therapy was reported in this press release from the National Cancer Institute on July 16, 2002. In this media advisory dated July 9, 2002, American Heart Association President Robert Bonow M.D. Responds to New Findings From Women's Health Initiative Trial, AHA President Robert Bonow, MD states that, "Based on current evidence, the American Heart Association advises that women do not start or continue combined HRT for the prevention of coronary heart disease." |
| Natural Alternatives to Hormone Replacement Therapy - EstrAval ® |
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The article, Natural Alternatives to Hormone Replacement Therapy, an article on the AHealthyMe web site, lists the benefits of black cohosh and donq quai, but cautions about the safety of many over-the-counter herbal cocktails and suggests seeking advice for using appropriate combinations. (The AHealthyMe website is produced by Blue Cross Blue Shield of Massachusetts and is a database of health articles and reference materials from respected medical journals and consumer publications.) In this study were three groups of women, one using HRT alone, a second using a combination of HRT and supplements, and the third using supplements (soy, ginkgo biloba and black cohosh). Perceived quality of life and overall control of menopausal symptoms were highest among women using dietary supplements alone, with those using combination therapy second highest. Dietary supplement use among menopausal women attending a San Francisco health conference. |
| Menopause Support with Soy |
| In the article Menopause and Soy, Dr. Clare M. Hasler cites several studies on the efficacy of soy in menopausal women. (Dr. Clare M. Hasler received her B.S. in Human Nutrition from Michigan State University in 1981 and M.S. in Nutrition Science from The Pennsylvania State University in 1984. In 1990, she was awarded a dual Ph.D. in Environmental Toxicology and Human Nutrition from Michigan State University. From 1990-1992, Dr. Hasler was a postdoctoral fellow in the Laboratory of Cellular Carcinogenesis and Tumor Promotion at the National Cancer Institute, National Institutes of Health, Bethesda, MD. Her current research activities are focused on the role of soy in chronic disease prevention. She teaches courses at both the undergraduate and graduate level on functional foods and the role of phytochemicals in disease prevention. Dr. Hasler writes extensively on functional foods and is a widely requested speaker on the topic by industry, academia and the media. She was recently recognized by Self magazine as one of the "Top 25 Food Influentials".)
Some medical journal abstracts on soy: |
| Black Cohosh and Dong Quai Herbal Menopause Support |
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An excellent article from the Gale Encyclopedia of Alternative Medicine, Black Cohosh, cites several studies concluding the efficacy and safety of this herb. (The Gale Encyclopedia of Alternative Medicine, released in November 2000, consists of four volumes of current, unbiased information on alternative and complementary medical practices. Information on recommended therapies for 275 specific disorders and diseases, and on medicinal uses for plants and herbs are balanced by conclusions of studies on efficacy and analysis of current levels of acceptance by traditional scientists and doctors. This resource is published by The Gale Group, a world leader in e-information publishing for libraries, schools and businesses. Best known for its accurate and authoritative reference content as well as its intelligent organization of full-text magazine and newspaper articles, the company creates and maintains more than 600 databases that are published online, in print and in microform. Its online Health & Wellness Resource Center is accessed by the public, university and medical libraries via subscription.) Some medical journal abstracts in the databases of National Center for Biotechnology Information (NCBI), a division of the National Library of Medicine (NLM) at the National Institutes of Health (NIH): Physiological investigation of a unique extract of black cohosh (Cimicifugae racemosae rhizoma): a 6-month clinical study demonstrates no systemic estrogenic effect |
| Comments From Your Researcher |
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